Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway

BACKGROUND: Detachment of epithelial cells from the extracellular matrix initiates programmed cell death by a process termed anoikis. Malignant cells must acquire anoikis resistance to leave the primary tumour and metastasise. Multiple signal transduction pathways can activate anoikis and confer ano...

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Detalles Bibliográficos
Autores principales: Luey, Brendan C., May, Felicity E. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722749/
https://www.ncbi.nlm.nih.gov/pubmed/26801096
http://dx.doi.org/10.1186/s12943-015-0482-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722749/
https://www.ncbi.nlm.nih.gov/pubmed/26801096
http://dx.doi.org/10.1186/s12943-015-0482-2

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