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Optimization of canine interleukin-12 production using a baculovirus insect cell expression system

BACKGROUND: Interleukin-12 is an important cytokine in mediating cellular immune responses. RESULTS: Recombinant single-chain canine IL-12 was produced in a baculovirus-insect cell system with the aim of conducting further studies on modulation of immune responses in dogs. To optimize the production...

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Detalles Bibliográficos
Autores principales: de Pinheiro, Cristiane Garboggini Melo, Pedrosa, Mayara de Oliveira, Teixeira, Naiara Carvalho, Ano Bom, Ana Paula Dinis, van Oers, Monique M., Oliveira, Geraldo Gileno de Sá
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722752/
https://www.ncbi.nlm.nih.gov/pubmed/26795376
http://dx.doi.org/10.1186/s13104-016-1843-7