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Optimization of canine interleukin-12 production using a baculovirus insect cell expression system
BACKGROUND: Interleukin-12 is an important cytokine in mediating cellular immune responses. RESULTS: Recombinant single-chain canine IL-12 was produced in a baculovirus-insect cell system with the aim of conducting further studies on modulation of immune responses in dogs. To optimize the production...
Autores principales: | de Pinheiro, Cristiane Garboggini Melo, Pedrosa, Mayara de Oliveira, Teixeira, Naiara Carvalho, Ano Bom, Ana Paula Dinis, van Oers, Monique M., Oliveira, Geraldo Gileno de Sá |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722752/ https://www.ncbi.nlm.nih.gov/pubmed/26795376 http://dx.doi.org/10.1186/s13104-016-1843-7 |
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