Targeting cryptic epitope with modified antigen coupled to the surface of liposomes induces strong antitumor CD8 T-cell immune responses in vivo

Active cancer immunotherapy, such as cancer vaccine, is based on the fundamental knowledge that tumor-associated antigens (TAAs) are presented on MHC molecules for recognition by specific T cells. However, most TAAs are self-antigens and are also expressed on normal tissues, including the thymus. Th...

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Detalles Bibliográficos
Autores principales: HORIUCHI, YUTAKA, TAKAGI, AKIRA, UCHIDA, TETSUYA, AKATSUKA, TOSHITAKA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722887/
https://www.ncbi.nlm.nih.gov/pubmed/26398429
http://dx.doi.org/10.3892/or.2015.4299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722887/
https://www.ncbi.nlm.nih.gov/pubmed/26398429
http://dx.doi.org/10.3892/or.2015.4299

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