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Site-Directed Mutagenesis to Improve Sensitivity of a Synthetic Two-Component Signaling System
Two-component signaling (2CS) systems enable bacterial cells to respond to changes in their local environment, often using a membrane-bound sensor protein and a cytoplasmic responder protein to regulate gene expression. Previous work has shown that Escherichia coli’s natural EnvZ/OmpR 2CS could be m...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723039/ https://www.ncbi.nlm.nih.gov/pubmed/26799494 http://dx.doi.org/10.1371/journal.pone.0147494 |