Vascular Endothelium-Dependent and Independent Actions of Oleanolic Acid and Its Synthetic Oleanane Derivatives as Possible Mechanisms for Hypotensive Effects

PURPOSE: Plant-derived oleanolic acid (OA) and its related synthetic derivatives (Br-OA and Me-OA) possess antihypertensive effects in experimental animals. The present study investigated possible underlying mechanisms in rat isolated single ventricular myocytes and in vascular smooth muscles superf...

Descripción completa

Detalles Bibliográficos
Autores principales: Madlala, Hlengiwe P., Metzinger, Thomas, van Heerden, Fanie R., Musabayane, Cephas T., Mubagwa, Kanigula, Dessy, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723044/
https://www.ncbi.nlm.nih.gov/pubmed/26799746
http://dx.doi.org/10.1371/journal.pone.0147395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723044/
https://www.ncbi.nlm.nih.gov/pubmed/26799746
http://dx.doi.org/10.1371/journal.pone.0147395

Ejemplares similares