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Vascular Endothelium-Dependent and Independent Actions of Oleanolic Acid and Its Synthetic Oleanane Derivatives as Possible Mechanisms for Hypotensive Effects

PURPOSE: Plant-derived oleanolic acid (OA) and its related synthetic derivatives (Br-OA and Me-OA) possess antihypertensive effects in experimental animals. The present study investigated possible underlying mechanisms in rat isolated single ventricular myocytes and in vascular smooth muscles superf...

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Detalles Bibliográficos
Autores principales:	Madlala, Hlengiwe P., Metzinger, Thomas, van Heerden, Fanie R., Musabayane, Cephas T., Mubagwa, Kanigula, Dessy, Chantal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723044/ https://www.ncbi.nlm.nih.gov/pubmed/26799746 http://dx.doi.org/10.1371/journal.pone.0147395

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