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Rapid and Highly Sensitive Detection of Variant Creutzfeldt - Jakob Disease Abnormal Prion Protein on Steel Surfaces by Protein Misfolding Cyclic Amplification: Application to Prion Decontamination Studies

The prevalence of variant Creutzfeldt-Jakob disease (vCJD) in the population remains uncertain, although it has been estimated that 1 in 2000 people in the United Kingdom are positive for abnormal prion protein (PrP(TSE)) by a recent survey of archived appendix tissues. The prominent lymphotropism o...

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Detalles Bibliográficos
Autores principales: Belondrade, Maxime, Nicot, Simon, Béringue, Vincent, Coste, Joliette, Lehmann, Sylvain, Bougard, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723062/
https://www.ncbi.nlm.nih.gov/pubmed/26800081
http://dx.doi.org/10.1371/journal.pone.0146833