Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice

CAR is a transmembrane protein that is expressed in various epithelial and endothelial cells. CAR mediates adenoviral infection, as well as adenovirus-mediated oncolysis of AxdAdB-3, an E1A/E1B double-restricted oncolytic adenovirus, in prostate cancer cells. This study further assessed the therapeu...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yue-Hong, Yang, Fei, Wang, Hua, Cai, Zhi-Jian, Xu, Yi-Peng, Zhao, An, Su, Ying, Zhang, Gu, Zhu, Shao-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723068/
https://www.ncbi.nlm.nih.gov/pubmed/26799485
http://dx.doi.org/10.1371/journal.pone.0147173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723068/
https://www.ncbi.nlm.nih.gov/pubmed/26799485
http://dx.doi.org/10.1371/journal.pone.0147173

Ejemplares similares