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Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice

CAR is a transmembrane protein that is expressed in various epithelial and endothelial cells. CAR mediates adenoviral infection, as well as adenovirus-mediated oncolysis of AxdAdB-3, an E1A/E1B double-restricted oncolytic adenovirus, in prostate cancer cells. This study further assessed the therapeu...

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Detalles Bibliográficos
Autores principales:	Shen, Yue-Hong, Yang, Fei, Wang, Hua, Cai, Zhi-Jian, Xu, Yi-Peng, Zhao, An, Su, Ying, Zhang, Gu, Zhu, Shao-Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723068/ https://www.ncbi.nlm.nih.gov/pubmed/26799485 http://dx.doi.org/10.1371/journal.pone.0147173

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