Cargando…

Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice

BACKGROUND: Serotonin (5-hydroxytryptamin, 5-HT) is an indolamine platelet agonist, biochemically derived from tryptophan. 5-HT is secreted from the enterochromaffin cells into the gastrointestinal tract and blood. Blood 5-HT has been proposed to regulate hemostasis by acting as a vasoconstrictor an...

Descripción completa

Detalles Bibliográficos
Autores principales: Wolf, Karen, Braun, Attila, Haining, Elizabeth J., Tseng, Yu-Lun, Kraft, Peter, Schuhmann, Michael K., Gotru, Sanjeev K., Chen, Wenchun, Hermanns, Heike M., Stoll, Guido, Lesch, Klaus-Peter, Nieswandt, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723080/
https://www.ncbi.nlm.nih.gov/pubmed/26800051
http://dx.doi.org/10.1371/journal.pone.0147664