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Genetic Evidence for Genotoxic Effect of Entecavir, an Anti-Hepatitis B Virus Nucleotide Analog

Nucleoside analogues (NAs) have been the most frequently used treatment option for chronic hepatitis B patients. However, they may have genotoxic potentials due to their interference with nucleic acid metabolism. Entecavir, a deoxyguanosine analog, is one of the most widely used oral antiviral NAs a...

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Detalles Bibliográficos
Autores principales: Jiang, Lei, Wu, Xiaohua, He, Fang, Liu, Ying, Hu, Xiaoqing, Takeda, Shunichi, Qing, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723259/
https://www.ncbi.nlm.nih.gov/pubmed/26800464
http://dx.doi.org/10.1371/journal.pone.0147440