Regulation of VEGF by mevalonate pathway inhibition in breast cancer

Aminobisphosphonates are used for the treatment of benign and malignant bone disorders. As inhibitors of the mevalonate pathway they exert direct anti-tumor effects in vitro and in preclinical models of bone metastases. Bisphosphonates are thought to have an anti-angiogenic activity as decreased lev...

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Detalles Bibliográficos
Autores principales: Rachner, Tilman D., Göbel, Andy, Junker, Maria, Hötzel, Josefa, Benad-Mehner, Peggy, Hadji, Peyman, Hofbauer, Lorenz C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723384/
https://www.ncbi.nlm.nih.gov/pubmed/26909280
http://dx.doi.org/10.1016/j.jbo.2013.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723384/
https://www.ncbi.nlm.nih.gov/pubmed/26909280
http://dx.doi.org/10.1016/j.jbo.2013.05.003

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