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The SK-N-AS human neuroblastoma cell line develops osteolytic bone metastases with increased angiogenesis and COX-2 expression

Neuroblastoma (NB), which arises from embryonic neural crest cells, is the most common extra-cranial solid tumor of childhood. Approximately half of NB patients manifest bone metastasis accompanied with bone pain, fractures and bone marrow failure, leading to disturbed quality of life and poor survi...

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Detalles Bibliográficos
Autores principales: Tsutsumimoto, Takahiro, Williams, Paul, Yoneda, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723652/
https://www.ncbi.nlm.nih.gov/pubmed/26909300
http://dx.doi.org/10.1016/j.jbo.2014.10.002