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High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission

Preventing transmission is an important element of malaria control. However, most of the current available methods to assay for malaria transmission blocking are relatively low throughput and cannot be applied to large chemical libraries. We have developed a high-throughput and cost-effective assay,...

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Detalles Bibliográficos
Autores principales: Plouffe, David M., Wree, Melanie, Du, Alan Y., Meister, Stephan, Li, Fengwu, Patra, Kailash, Lubar, Aristea, Okitsu, Shinji L., Flannery, Erika L., Kato, Nobutaka, Tanaseichuk, Olga, Comer, Eamon, Zhou, Bin, Kuhen, Kelli, Zhou, Yingyao, Leroy, Didier, Schreiber, Stuart L., Scherer, Christina A., Vinetz, Joseph, Winzeler, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723716/
https://www.ncbi.nlm.nih.gov/pubmed/26749441
http://dx.doi.org/10.1016/j.chom.2015.12.001