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Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models

BACKGROUND: The phase 3 trial of the RTS,S/AS01 malaria vaccine candidate showed modest efficacy of the vaccine against Plasmodium falciparum malaria, but was not powered to assess mortality endpoints. Impact projections and cost-effectiveness estimates for longer timeframes than the trial follow-up...

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Detalles Bibliográficos
Autores principales: Penny, Melissa A, Verity, Robert, Bever, Caitlin A, Sauboin, Christophe, Galactionova, Katya, Flasche, Stefan, White, Michael T, Wenger, Edward A, Van de Velde, Nicolas, Pemberton-Ross, Peter, Griffin, Jamie T, Smith, Thomas A, Eckhoff, Philip A, Muhib, Farzana, Jit, Mark, Ghani, Azra C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723722/
https://www.ncbi.nlm.nih.gov/pubmed/26549466
http://dx.doi.org/10.1016/S0140-6736(15)00725-4