Cargando…

Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control

BACKGROUND: Most mammalian genes display alternative cleavage and polyadenylation (APA). Previous studies have indicated preferential expression of APA isoforms with short 3’ untranslated regions (3’UTRs) in testes. RESULTS: By deep sequencing of the 3’ end region of poly(A) + transcripts, we report...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wencheng, Park, Ji Yeon, Zheng, Dinghai, Hoque, Mainul, Yehia, Ghassan, Tian, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724118/
https://www.ncbi.nlm.nih.gov/pubmed/26801249
http://dx.doi.org/10.1186/s12915-016-0229-6