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Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control
BACKGROUND: Most mammalian genes display alternative cleavage and polyadenylation (APA). Previous studies have indicated preferential expression of APA isoforms with short 3’ untranslated regions (3’UTRs) in testes. RESULTS: By deep sequencing of the 3’ end region of poly(A) + transcripts, we report...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724118/ https://www.ncbi.nlm.nih.gov/pubmed/26801249 http://dx.doi.org/10.1186/s12915-016-0229-6 |