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Vascular biomarkers derived from dynamic contrast-enhanced MRI predict response of vestibular schwannoma to antiangiogenic therapy in type 2 neurofibromatosis

BACKGROUND: Antiangiogenic therapy of vestibular schwannoma (VS) in type 2 neurofibromatosis can produce tumor shrinkage with response rates of 40%–60%. This study examines the predictive value of parameter-derived MRI in this setting. METHODS: Twelve patients with 20 VSs were recruited. Each had at...

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Detalles Bibliográficos
Autores principales: Li, Ka-Loh, Djoukhadar, Ibrahim, Zhu, Xiaoping, Zhao, Sha, Lloyd, Simon, McCabe, Martin, McBain, Catherine, Evans, D. Gareth, Jackson, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724182/
https://www.ncbi.nlm.nih.gov/pubmed/26311690
http://dx.doi.org/10.1093/neuonc/nov168