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Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program

DNA replication is temporally and spatially organized in all eukaryotes, yet the molecular control and biological function of the replication-timing program are unclear. Rif1 is required for normal genome-wide regulation of replication timing, but its molecular function is poorly understood. Here we...

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Detalles Bibliográficos
Autores principales: Foti, Rossana, Gnan, Stefano, Cornacchia, Daniela, Dileep, Vishnu, Bulut-Karslioglu, Aydan, Diehl, Sarah, Buness, Andreas, Klein, Felix A., Huber, Wolfgang, Johnstone, Ewan, Loos, Remco, Bertone, Paul, Gilbert, David M., Manke, Thomas, Jenuwein, Thomas, Buonomo, Sara C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724237/
https://www.ncbi.nlm.nih.gov/pubmed/26725008
http://dx.doi.org/10.1016/j.molcel.2015.12.001