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Wen-Xin Decoction ameliorates vascular endothelium dysfunction via the PI3K/AKT/eNOS pathway in experimental atherosclerosis in rats

BACKGROUND: Nitric oxide (NO) is the most powerful vasodilator that inhibits leukocyte adhesion, platelet aggregation, and vascular smooth muscle cell proliferation. However, excessive NO can cause lipid peroxidation and direct endothelial cell damage. Therefore, investigation of the role of NO in a...

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Detalles Bibliográficos
Autores principales: Li, Tongda, Li, Dongmei, Xu, Hui, Zhang, Huamin, Tang, Danli, Cao, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724402/
https://www.ncbi.nlm.nih.gov/pubmed/26803585
http://dx.doi.org/10.1186/s12906-016-1002-7