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Universal Poisson Statistics of mRNAs with Complex Decay Pathways
Messenger RNA (mRNA) dynamics in single cells are often modeled as a memoryless birth-death process with a constant probability per unit time that an mRNA molecule is synthesized or degraded. This predicts a Poisson steady-state distribution of mRNA number, in close agreement with experiments. This...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Biophysical Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724633/ https://www.ncbi.nlm.nih.gov/pubmed/26743048 http://dx.doi.org/10.1016/j.bpj.2015.12.001 |