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A direct approach to amines with remote stereocenters by enantioselective CuH-catalysed reductive relay hydroamination
Amines with remote stereocenters (stereocenters that are three or more bonds away from the C–N bond) are important structural elements in many pharmaceutical agents and natural products. However, previously reported methods to prepare these compounds in an enantioselective manner are indirect and re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724644/ https://www.ncbi.nlm.nih.gov/pubmed/26791897 http://dx.doi.org/10.1038/nchem.2418 |