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Phi29 Connector-DNA Interactions Govern DNA Crunching and Rotation, Supporting the Check-Valve Model

During replication of the ϕ29 bacteriophage inside a bacterial host cell, a DNA packaging motor transports the viral DNA into the procapsid against a pressure difference of up to 40 ± 20 atm. Several models have been proposed for the underlying molecular mechanism. Here we have used molecular dynami...

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Detalles Bibliográficos
Autores principales: Kumar, Rajendra, Grubmüller, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724654/
https://www.ncbi.nlm.nih.gov/pubmed/26789768
http://dx.doi.org/10.1016/j.bpj.2015.12.010