Development and validation of an HPLC–MS/MS method to determine clopidogrel in human plasma

A quantitative method for clopidogrel using online-SPE tandem LC–MS/MS was developed and fully validated according to the well-established FDA guidelines. The method achieves adequate sensitivity for pharmacokinetic studies, with lower limit of quantifications (LLOQs) as low as 10 pg/mL. Chromatogra...

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Detalles Bibliográficos
Autores principales: Liu, Gangyi, Dong, Chunxia, Shen, Weiwei, Lu, Xiaopei, Zhang, Mengqi, Gui, Yuzhou, Zhou, Qinyi, Yu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724691/
https://www.ncbi.nlm.nih.gov/pubmed/26904399
http://dx.doi.org/10.1016/j.apsb.2015.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724691/
https://www.ncbi.nlm.nih.gov/pubmed/26904399
http://dx.doi.org/10.1016/j.apsb.2015.11.001

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