MicroRNA‐27b suppresses tumor progression by regulating ARFGEF1 and focal adhesion signaling

The non‐receptor tyrosine kinase c‐Src is frequently activated during progression of colon cancers. In this study, we found that among the c‐Src‐regulated microRNAs (miRNAs), miR‐27b is also repressed by activation of K‐Ras/H‐Ras. Inhibitor studies suggested that the phosphatidylinositol 3‐kinase pa...

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Detalles Bibliográficos
Autores principales: Matsuyama, Rei, Okuzaki, Daisuke, Okada, Masato, Oneyama, Chitose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724816/
https://www.ncbi.nlm.nih.gov/pubmed/26473412
http://dx.doi.org/10.1111/cas.12834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724816/
https://www.ncbi.nlm.nih.gov/pubmed/26473412
http://dx.doi.org/10.1111/cas.12834

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