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Quantitative Correlation of Conformational Binding Enthalpy with Substrate Specificity of Serine Proteases
[Image: see text] Members of the same protease family show different substrate specificity, even if they share identical folds, depending on the physiological processes they are part of. Here, we investigate the key factors for subpocket and global specificity of factor Xa, elastase, and granzyme B...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724848/ https://www.ncbi.nlm.nih.gov/pubmed/26709959 http://dx.doi.org/10.1021/acs.jpcb.5b10637 |