miR-340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancer

MicroRNAs (miRNAs) control cell cycle progression by targeting the transcripts encoding for cyclins, CDKs and CDK inhibitors, such as p27(KIP1) (p27). p27 expression is controlled by multiple transcriptional and posttranscriptional mechanisms, including translational inhibition by miR-221/222 and po...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandez, Serena, Risolino, Maurizio, Mandia, Nadia, Talotta, Francesco, Soini, Ylermi, Incoronato, Mariarosaria, Condorelli, Gerolama, Banfi, Sandro, Verde, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724947/
https://www.ncbi.nlm.nih.gov/pubmed/25151966
http://dx.doi.org/10.1038/onc.2014.267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724947/
https://www.ncbi.nlm.nih.gov/pubmed/25151966
http://dx.doi.org/10.1038/onc.2014.267

Ejemplares similares