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EV71 virus-like particles produced by co-expression of capsid proteins in yeast cells elicit humoral protective response against EV71 lethal challenge

BACKGROUND: Enterovirus 71 (EV71) is the most common causative pathogens of hand, foot and mouth disease (HFMD) associated with severe neurological complications. There is a great need to develop prophylactic vaccine against EV71 infection. RESULTS: EV71 virus-like particle (VLP) was produced in yea...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowen, Xiao, Xiangqian, Zhao, Miao, Liu, Wei, Pang, Lin, Sun, Xin, Cen, Shan, Yang, Burton B., Huang, Yuming, Sheng, Wang, Zeng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724958/
https://www.ncbi.nlm.nih.gov/pubmed/26809443
http://dx.doi.org/10.1186/s13104-015-1780-x