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Gene Deletion by Fluorescence-Reported Allelic Exchange Mutagenesis in Chlamydia trachomatis

Although progress in Chlamydia genetics has been rapid, genomic modification has previously been limited to point mutations and group II intron insertions which truncate protein products. The bacterium has thus far been intractable to gene deletion or more-complex genomic integrations such as alleli...

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Detalles Bibliográficos
Autores principales: Mueller, Konrad E., Wolf, Katerina, Fields, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725004/
https://www.ncbi.nlm.nih.gov/pubmed/26787828
http://dx.doi.org/10.1128/mBio.01817-15