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Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans

Influenza remains a major global health burden. Seasonal vaccines offer protection but can be rendered less effective when the virus undergoes extensive antigenic drift. Antibodies that target the highly conserved hemagglutinin stalk can protect against drifted viruses, and vaccine constructs design...

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Detalles Bibliográficos
Autores principales: Nachbagauer, Raffael, Choi, Angela, Izikson, Ruvim, Cox, Manon M., Palese, Peter, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725014/
https://www.ncbi.nlm.nih.gov/pubmed/26787832
http://dx.doi.org/10.1128/mBio.01996-15