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Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans
Influenza remains a major global health burden. Seasonal vaccines offer protection but can be rendered less effective when the virus undergoes extensive antigenic drift. Antibodies that target the highly conserved hemagglutinin stalk can protect against drifted viruses, and vaccine constructs design...
Autores principales: | Nachbagauer, Raffael, Choi, Angela, Izikson, Ruvim, Cox, Manon M., Palese, Peter, Krammer, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725014/ https://www.ncbi.nlm.nih.gov/pubmed/26787832 http://dx.doi.org/10.1128/mBio.01996-15 |
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