Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death

The pseudokinase mixed lineage kinase domain-like (MLKL) is an essential effector of necroptotic cell death. Two distinct human MLKL isoforms have previously been reported, but their capacities to trigger cell death have not been compared directly. Herein, we examine these two MLKL isoforms, and fur...

Descripción completa

Detalles Bibliográficos
Autores principales: Arnež, Katja Hrovat, Kindlova, Michaela, Bokil, Nilesh J., Murphy, James M., Sweet, Matthew J., Gunčar, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725247/
https://www.ncbi.nlm.nih.gov/pubmed/26704887
http://dx.doi.org/10.1042/BSR20150246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725247/
https://www.ncbi.nlm.nih.gov/pubmed/26704887
http://dx.doi.org/10.1042/BSR20150246

Ejemplares similares