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Genes implicated in stem cell identity and temporal programme are directly targeted by Notch in neuroblast tumours
Notch signalling is involved in a multitude of developmental decisions and its aberrant activation is linked to many diseases, including cancers. One example is the neural stem cell tumours that arise from constitutive Notch activity in Drosophila neuroblasts. To investigate how hyperactivation of N...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725341/ https://www.ncbi.nlm.nih.gov/pubmed/26657768 http://dx.doi.org/10.1242/dev.126326 |