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Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain

The use of chemoprotective agents to minimize the side effects of the chemotherapy, primarily via activation of the Nrf2 pathway, is an emerging research field, which has attracted broad attention from both academia and pharmaceutical industry. Through high-throughput chemical screens we have disclo...

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Detalles Bibliográficos
Autores principales: Dong, Ting, Liu, Weilong, Shen, Zhirong, Li, Lin, Chen, She, Lei, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725373/
https://www.ncbi.nlm.nih.gov/pubmed/26757824
http://dx.doi.org/10.1038/srep19231