Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

We have developed the CD44v6-targeting human bivalent antibody fragment AbD19384, an engineered recombinant human bivalent Fab antibody formed via dimerization of dHLX (synthetic double helix loop helix motif) domains, for potential use in antibody-based molecular imaging of squamous cell carcinoma...

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Detalles Bibliográficos
Autores principales: HAYLOCK, ANNA-KARIN, SPIEGELBERG, DIANA, MORTENSEN, ANJA C., SELVARAJU, RAM K., NILVEBRANT, JOHAN, ERIKSSON, OLOF, TOLMACHEV, VLADIMIR, NESTOR, MARIKA V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725455/
https://www.ncbi.nlm.nih.gov/pubmed/26676731
http://dx.doi.org/10.3892/ijo.2015.3290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725455/
https://www.ncbi.nlm.nih.gov/pubmed/26676731
http://dx.doi.org/10.3892/ijo.2015.3290

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