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Common Polymorphisms in the Solute Carrier SLC30A10 are Associated With Blood Manganese and Neurological Function

Manganese (Mn) is an essential nutrient in humans, but excessive exposure to Mn may cause neurotoxicity. Despite homeostatic regulation, Mn concentrations in blood vary considerably among individuals. We evaluated if common single-nucleotide polymorphisms (SNPs) in SLC30A10, which likely encodes an...

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Detalles Bibliográficos
Autores principales: Wahlberg, Karin, Kippler, Maria, Alhamdow, Ayman, Rahman, Syed Moshfiqur, Smith, Donald R., Vahter, Marie, Lucchini, Roberto G., Broberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725612/
https://www.ncbi.nlm.nih.gov/pubmed/26628504
http://dx.doi.org/10.1093/toxsci/kfv252