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Anionic clay as the drug delivery vehicle: tumor targeting function of layered double hydroxide-methotrexate nanohybrid in C33A orthotopic cervical cancer model

Methotrexate (MTX), an anticancer agent, was successfully intercalated into the anionic clay, layered double hydroxides to form a new nanohybrid drug. The coprecipitation and subsequent hydrothermal method were used to prepare chemically, structurally, and morphologically well-defined two-dimensiona...

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Detalles Bibliográficos
Autores principales: Choi, Goeun, Piao, Huiyan, Alothman, Zeid A, Vinu, Ajayan, Yun, Chae-Ok, Choy, Jin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725630/
https://www.ncbi.nlm.nih.gov/pubmed/26855572
http://dx.doi.org/10.2147/IJN.S95611