Depot injectable atorvastatin biodegradable in situ gel: development, optimization, in vitro, and in vivo evaluation

This study aimed to develop an optimized depot injectable atorvastatin (ATR) biodegradable in situ gel (ISG) system with minimum initial burst using a central composite design. The factors selected were poly (d, l-lactide-co-glycolide) (PLGA) concentration (X(1)), molecular weight of polyethylene gl...

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Detalles Bibliográficos
Autores principales: Ahmed, Tarek A, Alharby, Yasser A, El-Helw, Abdel-Rahim M, Hosny, Khaled M, El-Say, Khalid M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725642/
https://www.ncbi.nlm.nih.gov/pubmed/26855565
http://dx.doi.org/10.2147/DDDT.S98078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725642/
https://www.ncbi.nlm.nih.gov/pubmed/26855565
http://dx.doi.org/10.2147/DDDT.S98078

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