Targeted modulation of cell differentiation in distinct regions of the gastrointestinal tract via oral administration of differently PEG-PEI functionalized mesoporous silica nanoparticles

Targeted delivery of drugs is required to efficiently treat intestinal diseases such as colon cancer and inflammation. Nanoparticles could overcome challenges in oral administration caused by drug degradation at low pH and poor permeability through mucus layers, and offer targeted delivery to diseas...

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Detalles Bibliográficos
Autores principales: Desai, Diti, Prabhakar, Neeraj, Mamaeva, Veronika, Karaman, Didem Şen, Lähdeniemi, Iris AK, Sahlgren, Cecilia, Rosenholm, Jessica M, Toivola, Diana M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725644/
https://www.ncbi.nlm.nih.gov/pubmed/26855569
http://dx.doi.org/10.2147/IJN.S94013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725644/
https://www.ncbi.nlm.nih.gov/pubmed/26855569
http://dx.doi.org/10.2147/IJN.S94013

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