Durable Disease Control with MEK Inhibition in a Patient with NRAS-mutated Atypical Chronic Myeloid Leukemia

Atypical chronic myeloid leukemia (aCML) and chronic neutrophilic leukemia (CNL) are rare hematologic neoplasms characterized by leukocytosis and a hypercellular bone marrow. Although recurrent mutations in the colony-stimulating factor 3 receptor (CSF3R) are frequently observed in patients with (CN...

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Detalles Bibliográficos
Autores principales: Khanna, Vishesh, Pierce, Scott T, Dao, Kim-Hien T, Tognon, Cristina E, Hunt, David E, Junio, Brian, Tyner, Jeffrey W, Druker, Brian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725740/
https://www.ncbi.nlm.nih.gov/pubmed/26870618
http://dx.doi.org/10.7759/cureus.414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725740/
https://www.ncbi.nlm.nih.gov/pubmed/26870618
http://dx.doi.org/10.7759/cureus.414

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