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Durable Disease Control with MEK Inhibition in a Patient with NRAS-mutated Atypical Chronic Myeloid Leukemia
Atypical chronic myeloid leukemia (aCML) and chronic neutrophilic leukemia (CNL) are rare hematologic neoplasms characterized by leukocytosis and a hypercellular bone marrow. Although recurrent mutations in the colony-stimulating factor 3 receptor (CSF3R) are frequently observed in patients with (CN...
Autores principales: | Khanna, Vishesh, Pierce, Scott T, Dao, Kim-Hien T, Tognon, Cristina E, Hunt, David E, Junio, Brian, Tyner, Jeffrey W, Druker, Brian J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725740/ https://www.ncbi.nlm.nih.gov/pubmed/26870618 http://dx.doi.org/10.7759/cureus.414 |
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