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Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Diverse Origin Target the Human Terminal Complement Inhibitor Vitronectin via a Single Common Motif

Pathogenicity of many microbes relies on their capacity to resist innate immunity, and to survive and persist in an immunocompetent human host microbes have developed highly efficient and sophisticated complement evasion strategies. Here we show that different human pathogens including Gram-negative...

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Detalles Bibliográficos
Autores principales: Hallström, Teresia, Singh, Birendra, Kraiczy, Peter, Hammerschmidt, Sven, Skerka, Christine, Zipfel, Peter F., Riesbeck, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725753/
https://www.ncbi.nlm.nih.gov/pubmed/26808444
http://dx.doi.org/10.1371/journal.pone.0147709