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FAS rs2234767 and rs1800682 polymorphisms jointly contributed to risk of colorectal cancer by affecting SP1/STAT1 complex recruitment to chromatin

FAS rs2234767 (−1377 G>A), rs1800682 (−670 A>G) and FASLG rs763110 (−844 C>T) promoter polymorphisms can influence transcriptional activities of the genes and thus multiple tumors susceptibility. To investigate their association with risk of colorectal cancer (CRC), the three SNPs were geno...

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Detalles Bibliográficos
Autores principales: Wang, Shizhi, Wu, Shenshen, Meng, Qingtao, Li, Xiaobo, Zhang, Jinchun, Chen, Rui, Wang, Meilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725756/
https://www.ncbi.nlm.nih.gov/pubmed/26759270
http://dx.doi.org/10.1038/srep19229