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Multistep assembly of DNA condensation clusters by SMC

SMC (structural maintenance of chromosomes) family members play essential roles in chromosome condensation, sister chromatid cohesion and DNA repair. It remains unclear how SMCs structure chromosomes and how their mechanochemical cycle regulates their interactions with DNA. Here we used single-molec...

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Detalles Bibliográficos
Autores principales: Kim, HyeongJun, Loparo, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725763/
https://www.ncbi.nlm.nih.gov/pubmed/26725510
http://dx.doi.org/10.1038/ncomms10200