F-actin mechanics control spindle centring in the mouse zygote

Mitotic spindle position relies on interactions between astral microtubules nucleated by centrosomes and a rigid cortex. Some cells, such as mouse oocytes, do not possess centrosomes and astral microtubules. These cells rely only on actin and on a soft cortex to position their spindle off-centre and...

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Detalles Bibliográficos
Autores principales: Chaigne, Agathe, Campillo, Clément, Voituriez, Raphaël, Gov, Nir S., Sykes, Cécile, Verlhac, Marie-Hélène, Terret, Marie-Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725770/
https://www.ncbi.nlm.nih.gov/pubmed/26727405
http://dx.doi.org/10.1038/ncomms10253