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A Signaling Lipid Associated with Alzheimer’s Disease Promotes Mitochondrial Dysfunction

Fundamental changes in the composition and distribution of lipids within the brain are believed to contribute to the cognitive decline associated with Alzheimer’s disease (AD). The mechanisms by which these changes in lipid composition affect cellular function and ultimately cognition are not well u...

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Detalles Bibliográficos
Autores principales: Kennedy, Michael A., Moffat, Tia C., Gable, Kenneth, Ganesan, Suriakarthiga, Niewola-Staszkowska, Karolina, Johnston, Anne, Nislow, Corey, Giaever, Guri, Harris, Linda J., Loewith, Robbie, Zaremberg, Vanina, Harper, Mary-Ellen, Dunn, Teresa, Bennett, Steffany A. L., Baetz, Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725818/
https://www.ncbi.nlm.nih.gov/pubmed/26757638
http://dx.doi.org/10.1038/srep19332