Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries

Polycystic ovarian syndrome (PCOS) is associated with hyperhomocysteinemia and polycystic ovaries (PCO) usually produce oocytes of poor quality. However, the intracellular mechanism linking hyperhomocysteinemia and oocyte quality remains elusive. In this study, the quality of the oocytes isolated fr...

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Detalles Bibliográficos
Autores principales: Jia, Longfei, Li, Juan, He, Bin, Jia, Yimin, Niu, Yingjie, Wang, Chenfei, Zhao, Ruqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725837/
https://www.ncbi.nlm.nih.gov/pubmed/26758245
http://dx.doi.org/10.1038/srep19436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725837/
https://www.ncbi.nlm.nih.gov/pubmed/26758245
http://dx.doi.org/10.1038/srep19436

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