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Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis

Necroptosis as a molecular program, rather than simply incidental cell death, was established by elucidating the roles of receptor interacting protein (RIP) kinases 1 and 3, along with their downstream partner, mixed lineage kinase-like domain protein (MLKL). Previous studies suggested that phosphog...

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Detalles Bibliográficos
Autores principales: Lu, Wei, Sun, Junhui, Yoon, Jeong Seon, Zhang, Yan, Zheng, Lixin, Murphy, Elizabeth, Mattson, Mark P., Lenardo, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725845/
https://www.ncbi.nlm.nih.gov/pubmed/26807733
http://dx.doi.org/10.1371/journal.pone.0147792