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Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis
Necroptosis as a molecular program, rather than simply incidental cell death, was established by elucidating the roles of receptor interacting protein (RIP) kinases 1 and 3, along with their downstream partner, mixed lineage kinase-like domain protein (MLKL). Previous studies suggested that phosphog...
Autores principales: | Lu, Wei, Sun, Junhui, Yoon, Jeong Seon, Zhang, Yan, Zheng, Lixin, Murphy, Elizabeth, Mattson, Mark P., Lenardo, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725845/ https://www.ncbi.nlm.nih.gov/pubmed/26807733 http://dx.doi.org/10.1371/journal.pone.0147792 |
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